The Difference Between Piracetam and Noopept: Which One is the Best?

Lately there has been a lot of controversy regarding a class of supplements called Nootropics. These supplements have been used to help users improve cognitive function, memory, learning, retention, and many other mental functions. Nootropics are any substances that improve cognition, and in Greek literally meaning mind-turning. Two of the most common Nootropics arePiracetamandNoopept. But what do these supplements actually do? Are they safe? Click here to know more.

Piracetam Review

Piracetam(2-oxo-1-pyrrolidine-acetamide) is the most common of the nootropic drugs, as noted by There are many uses of the drug and some of the main benefits include improved learning, memory, brain metabolism, and capacity ( Piracetam is also known as Nootropil. Piracetam was synthesized by Corneliu E. Giurga in the 1960′s, from which he described it as a Nootropic, as the compound increased cognitive abilities and brain function. Piracetam works by improving the functioning of acetylcholine receptors and transmitters within the brain. Acetylcholine, itself is a powerful brain chemical that plays crucial roles in mood, memory, learning, and thought processes. By increasing levels of acetylcholine, Piracetam can have many positive effects.

The Difference Between Piracetam and Noopept

Noopept Review

Noopeptis one of the most popular Nootropic supplements out today, that is also rapidly gaining recognition. Noopept is highly regarded for its neuroprotective properties and cognitive enhancement. Noopept formulated in Russia, is a synthetic Nootropic molecule in the Racetam family, which very closely resembles Piracetam in effects. Noopept shows a much greater affinity for certain receptors in the brain, as a result a much smaller dose will see the same positive changes in cognitive ability.Noopeptis reported to be 1000x more potent than Piracetam. Noopept stimulates the release of neurotransmitters in the brain that help to boost brain power. This is one of the main benefits of Noopept that has become so popular for its users.

Piracetam Benefits

Piracetam is known to help improve communication between both hemispheres of the brain. Some of the benefits include improved memory, learning, more mental energy, enhanced cognition, improved focus, and higher levels of concentration. In regards to brain health, Piracetam also helps to protect the cerebral cortex against loss of oxygen. Piracetam has been used to help with older subjects in cognitive decline, especially after heart or brain surgery. More research is being performed for Piracetams effects on lowering depression and anxiety.

Noopept Benefits

One of the major benefits of Noopept is that, like Piracetam, it improves communication between your two hemispheres of your brain. It is also a neuroprotector, helping brain cells from too much damage. Noopept is very well known for its memory enhancing properties. Although some studies havent had enough positive results to obtain a concrete conclusion, many users have noticed a positive impact on learning and retaining information after taking Noopept. LikePiracetam, Noopept also benefits its users with enhanced cognition, increased alertness, focus, concentration, and mental energy. Users found that they read, write, and think with much less effort than normal. Some research has shown that mood is also affected in a positive way, reducing stress, mental fatigue, and anxiety.

Side Effects

Nootropics are considered safe, even by their definition. See the characteristics of Nootropics defined be C.Giurgea, who coined the term Nootropic below;

  • They should enhance learning and memory.
  • They should enhance the resistance of learned behaviors/memories to conditions which tend to disrupt them, like electroconvulsive shock, and hypoxia.
  • They should protect the brain against various physical or chemical injuries.
  • They should increase the efficacy of the tonic cortical/subcortical control mechanisms.
  • They should lack the usual pharmacology of other psychotropic drugs, like sedatives, or motor stimulants, and possess little to no side effects as well as extremely low levels of toxicity.

Let us note that MOST users do not experience side effects when using nootropics. In some rare cases some users have reported the following when taking Piracetam: weight gain, headaches, and nervousness. Noopept users, again in rare cases only, may experience nervousness, irritation, sedation, and emotional numbness. It should be noted that these rare cases usually result in supplementing the two in extremely high doses. It is important to follow the recommended dosing instructions given by your provider, or by following the below typical dosing.


So which is the best Nootropic? Piracetam? Noopept? This is a personal decision, and depends on the users goals for supplementing nootropics but both are brain enhancing drugs. Noopept is a newer, and stronger of the two with more advanced brain health properties. Piracetam has been around longer and therefore studied more heavily. Either or, they both have great benefits for your cognitive needs.

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